EFFECT OF DRILL QUALITY ON BIOLOGICAL DAMAGE IN BONE DRILLING

Effect of drill quality on biological damage in bone drilling

Abstract Bone drilling is a universal procedure in orthopaedics for fracture fixation, installing implants, or reconstructive surgery.Surgical drills are subjected to wear caused by their repeated use, thermal fatigue, irrigation with saline solution, and sterilization process.Wear of the cutting edges of a drill bit (worn drill) is detrimental for

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A p53-dependent response limits epidermal stem cell functionality and organismal size in mice with short telomeres.

Telomere maintenance is essential to ensure proper size and function of organs with a high turnover.In particular, a dwarf phenotype as well as phenotypes associated to premature loss of tissue regeneration, including the skin (hair loss, hair graying, decreased wound healing), are found in mice deficient for telomerase, the enzyme responsible for

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